Human outer dense fiber gene, ODF2, localizes to chromosome 9q34.

نویسندگان

  • X Shao
  • S Murthy
  • D J Demetrick
  • F A van der Hoorn
چکیده

We have isolated the human homolog of the rat Odf2 gene. In rat, Odf2, the 84-kDa major outer dense fiber protein, interacts strongly and specifically with Odf1, the 27-kDa major outer dense fiber protein. The interaction is mediated by leucine zippers during ODF assembly along the sperm axoneme. We compared homology and genomic structure to rat and mouse Odf2 genes. Using fluorescence in situ hybridization, we mapped the human Odf2 gene (ODF2) to chromosome 9q34.

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عنوان ژورنال:
  • Cytogenetics and cell genetics

دوره 83 3-4  شماره 

صفحات  -

تاریخ انتشار 1998